The Temperature Dependence of Hydrogen Bonds Is More Uniform in Stable Proteins: An Analysis of NMR h3JNC′ Couplings in Four Different Protein Structures

Long-range HNCO NMR spectra for proteins show crosspeaks due to 1JNC′, 2JNC′, 3JNCγ, and h3JNC′ couplings. The h3JNC′ couplings are transmitted through hydrogen bonds and their sizes are correlated to hydrogen bond lengths. We collected long-range HNCO data at a series of temperatures for four prote...

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Bibliographic Details
Main Authors: Alexandrescu, Andrei T., Dregni, Aurelio J.
Format: Article
Published: MDPI AG 2024
Online Access:https://hdl.handle.net/1721.1/155681