Unravelling the Antifibrinolytic Mechanism of Action of the 1,2,3-Triazole Derivatives

A new family of antifibrinolytic drugs has been recently discovered, combining a triazole moiety, an oxadiazolone, and a terminal amine. Two of the molecules of this family have shown activity that is greater than or similar to that of tranexamic acid (TXA), the current antifibrinolytic gold standar...

Full description

Bibliographic Details
Main Authors: Rabadà, Yvette, Bosch-Sanz, Oriol, Biarnés, Xevi, Pedreño, Javier, Caveda, Luis, Sánchez-García, David, Martorell, Jordi, Balcells, Mercedes
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Format: Article
Published: MDPI AG 2024
Online Access:https://hdl.handle.net/1721.1/155685