Detection of allele-specific expression in spatial transcriptomics with spASE

Detection of allele-specific expression in spatial transcriptomics with spASE

Spatial transcriptomics technologies permit the study of the spatial distribution of RNA at near-single-cell resolution genome-wide. However, the feasibility of studying spatial allele-specific expression (ASE) from these data remains uncharacterized. Here, we introduce spASE, a computational framew...

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Bibliographic Details
Main Authors: Zou, Luli S., Cable, Dylan M., Barrera-Lopez, Irving A., Zhao, Tongtong, Murray, Evan, Aryee, Martin J., Chen, Fei, Irizarry, Rafael A.
Other Authors: Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science
Format: Article
Language:English
Published: Springer Science and Business Media LLC 2024
Online Access:https://hdl.handle.net/1721.1/155698

Internet

https://hdl.handle.net/1721.1/155698

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