Transcriptomic changes in oligodendrocytes and precursor cells associate with clinical outcomes of Parkinson’s disease

Several prior studies have proposed the involvement of various brain regions and cell types in Parkinson’s disease (PD) pathology. Here, we performed snRNA-seq on the prefrontal cortex and anterior cingulate regions from a small cohort of post-mortem control and PD brain tissue. We found a significa...

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Bibliographic Details
Main Authors: Dehestani, Mohammad, Kozareva, Velina, Blauwendraat, Cornelis, Fraenkel, Ernest, Gasser, Thomas, Bansal, Vikas
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:English
Published: BioMed Central 2024
Online Access:https://hdl.handle.net/1721.1/156263