Developing a Contextual Annotation Framework for Short Linear Motifs in Proteins
Identifying and validating short linear motifs (SLiMs) is challenging due to their low sequence complexity and high prevalence across the proteome. Many false positives—sequences that match the pattern of the SLiM but are not involved in the biological functions typically associated with SLiMs—compl...
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| Format: | Thesis |
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Massachusetts Institute of Technology
2024
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| Online Access: | https://hdl.handle.net/1721.1/156589 |