Representation Learning Associates Patients’ Risks for Metabolic Diseases with Features of Their Lipocytes

Polygenic risk scores (PRS) estimate an individual’s risk of developing a certain disease, suggesting that differences between cells of individuals with high versus low PRS could give us insight into the cellular disease mechanisms. To study metabolic diseases, we analyze the distribution of cell st...

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Bibliographic Details
Main Author: Tan, Zipei
Other Authors: Uhler, Caroline
Format: Thesis
Published: Massachusetts Institute of Technology 2024
Online Access:https://hdl.handle.net/1721.1/156626
https://orcid.org/0009-0002-2864-4935