Representation Learning Associates Patients’ Risks for Metabolic Diseases with Features of Their Lipocytes
Polygenic risk scores (PRS) estimate an individual’s risk of developing a certain disease, suggesting that differences between cells of individuals with high versus low PRS could give us insight into the cellular disease mechanisms. To study metabolic diseases, we analyze the distribution of cell st...
Main Author: | Tan, Zipei |
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Other Authors: | Uhler, Caroline |
Format: | Thesis |
Published: |
Massachusetts Institute of Technology
2024
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Online Access: | https://hdl.handle.net/1721.1/156626 https://orcid.org/0009-0002-2864-4935 |
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