Structural Characterization of E22G Aβ1-42 Fibrils via 1H detected MAS NMR

Amyloid fibrils have been implicated in the pathogenesis of several neurodegenerative diseases, the most prevalent example being Alzheimer's disease (AD). Despite the prevalence of AD, relatively little is known about the structure of the associated amyloid fibrils. This has motivated our studi...

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Bibliographic Details
Main Authors: Golota, Natalie C., Michael, Brian, Saliba, Edward P., Linse, Sara, Griffin, Robert G.
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Published: Royal Society of Chemistry 2024
Online Access:https://hdl.handle.net/1721.1/156718