Silicone cryogel skeletons enhance the survival and mechanical integrity of hydrogel-encapsulated cell therapies

Silicone cryogel skeletons enhance the survival and mechanical integrity of hydrogel-encapsulated cell therapies

The transplantation of engineered cells that secrete therapeutic proteins presents a promising method for addressing a range of chronic diseases. However, hydrogels used to encase and protect non-autologous cells from immune rejection often suffer from poor mechanical properties, insufficient oxygen...

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Bibliographic Details
Main Authors: Jeang, William J, Bochenek, Matthew A, Bose, Suman, Zhao, Yichao, Wong, Bryan M, Yang, Jiawei, Jiang, Alexis L, Langer, Robert, Anderson, Daniel G
Other Authors: Massachusetts Institute of Technology. Department of Materials Science and Engineering
Format: Article
Language:English
Published: American Association for the Advancement of Science 2024
Online Access:https://hdl.handle.net/1721.1/156883

Internet

https://hdl.handle.net/1721.1/156883

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