Silicone cryogel skeletons enhance the survival and mechanical integrity of hydrogel-encapsulated cell therapies
The transplantation of engineered cells that secrete therapeutic proteins presents a promising method for addressing a range of chronic diseases. However, hydrogels used to encase and protect non-autologous cells from immune rejection often suffer from poor mechanical properties, insufficient oxygen...
Main Authors: | Jeang, William J, Bochenek, Matthew A, Bose, Suman, Zhao, Yichao, Wong, Bryan M, Yang, Jiawei, Jiang, Alexis L, Langer, Robert, Anderson, Daniel G |
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Other Authors: | Massachusetts Institute of Technology. Department of Materials Science and Engineering |
Format: | Article |
Language: | English |
Published: |
American Association for the Advancement of Science
2024
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Online Access: | https://hdl.handle.net/1721.1/156883 |
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