NAD depletion mediates cytotoxicity in human neurons with autophagy deficiency
Autophagy is a homeostatic process critical for cellular survival, and its malfunction is implicated in human diseases including neurodegeneration. Loss of autophagy contributes to cytotoxicity and tissue degeneration, but the mechanistic understanding of this phenomenon remains elusive. Here, we ge...
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| Format: | Article |
| Language: | English |
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Elsevier BV
2024
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| Online Access: | https://hdl.handle.net/1721.1/156897 |