Metabolic modulation to improve MSC expansion and therapeutic potential for articular cartilage repair

Background Articular cartilage degeneration can result from injury, age, or arthritis, causing significant joint pain and disability without surgical intervention. Currently, the only FDA cell-based therapy for articular cartilage injury is Autologous Chondrocyte Implantation (ACI);...

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Bibliographic Details
Main Authors: Tee, Ching A., Roxby, Daniel N., Othman, Rashidah, Denslin, Vinitha, Bhat, Kiseer S., Yang, Zheng, Han, Jongyoon, Tucker-Kellogg, Lisa, Boyer, Laurie A.
Other Authors: Singapore-MIT Alliance in Research and Technology (SMART)
Format: Article
Language:English
Published: BioMed Central 2024
Online Access:https://hdl.handle.net/1721.1/156927