Interpretable Computational Modeling of pre-mRNA Splicing for Multiple Eukaryotic Species
One of the key steps in eukaryotic gene expression is pre-mRNA splicing, whereby intronic sequences are excised from immature pre-mRNA transcripts and the remaining exonic sequences are joined together. This process is catalyzed by the spliceosome, a large complex of proteins and RNAs. A variety of...
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Format: | Thesis |
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Massachusetts Institute of Technology
2024
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Online Access: | https://hdl.handle.net/1721.1/156986 |