The rickettsial effector Sca4 has a conserved interaction with host clathrin and a tick cell specific role in infection
Intracellular bacterial pathogens secrete effectors to manipulate the host cell environment, create a hospitable niche, and promote infection. While many effectors interact with specific host machinery to perform a single distinct function, some effectors are capable of interaction with multiple hos...
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Format: | Thesis |
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Massachusetts Institute of Technology
2024
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Online Access: | https://hdl.handle.net/1721.1/157209 https://orcid.org/0000-0003-0774-5200 |