Regulation of the hif-1-dependent hypoxic stress response by C. elegans

All aerobic organisms need a way to sense oxygen levels and respond accordingly when in an unfavorable environment. In almost all metazoans, oxygen is both sensed and regulated by the HIF-1 (hypoxia inducible factor) transcription factor that is activated in periods of hypoxia and goes on to regulat...

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Bibliographic Details
Main Author: Diehl, Calista Sorine
Other Authors: Horvitz, H. Robert
Format: Thesis
Published: Massachusetts Institute of Technology 2024
Online Access:https://hdl.handle.net/1721.1/157246