Molecular, Genetic, and Process Approaches for Improving Secreted Pharmaceutical Protein Quality in Komagataella phaffii

Biopharmaceutical products constitute a significant portion of the global bioeconomy. Compared to traditional synthetic small-molecule drugs, recombinant therapeutic proteins offer advantages like enhanced specificity and reduced side effects, and there has been tremendous growth in their innovation...

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Bibliographic Details
Main Author: Yang, Yuchen
Other Authors: Love, J. Christopher
Format: Thesis
Published: Massachusetts Institute of Technology 2024
Online Access:https://hdl.handle.net/1721.1/157251