Aneuploid senescent cells activate NF-κB to promote their immune clearance by NK cells

The immune system plays a major role in the protection against cancer. Identifying and characterizing the pathways mediating this immune surveillance are thus critical for understanding how cancer cells are recognized and eliminated. Aneuploidy is a hallmark of cancer, and we previously found that u...

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Bibliographic Details
Main Authors: Wang, Ruoxi W., Viganò, Sonia, Ben-David, Uri, Amon, Angelika, Santaguida, Stefano
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:English
Published: Nature Publishing Group UK 2024
Online Access:https://hdl.handle.net/1721.1/157501