Ladder Polyether Synthesis via Epoxide-Opening Cascades Using a Disappearing Directing Group
The combination of a trimethylsilyl group, a Brønsted base, a fluoride source, and a hydroxylic solvent enables the first construction of the tetrad of tetrahydropyran rings found in the majority of the ladder polyether natural products by way of a cascade of epoxide-opening events that emulates the...
| Main Authors: | , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
American Chemical Society
2024
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| Online Access: | https://hdl.handle.net/1721.1/157513 |