Targeted hematopoietic stem cell depletion through SCF-blockade

Targeted hematopoietic stem cell depletion through SCF-blockade

Abstract Background Hematopoietic stem cell transplantation (HSCT) is a curative treatment for many diverse blood and immune diseases. However, HSCT regimens currently commonly utilize genotoxic chemotherapy and/or total body irradiation (TBI) conditioning which causes significant morbidity and mort...

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Bibliographic Details
Main Authors: Chan, Yan Y., Ho, Pui Y., Dib, Carla, Swartzrock, Leah, Rayburn, Maire, Willner, Hana, Ko, Ethan, Ho, Katie, Down, Julian D., Wilkinson, Adam C., Nakauchi, Hiro, Denis, Morgane, Cool, Taylor, Czechowicz, Agnieszka
Other Authors: Koch Institute for Integrative Cancer Research at MIT
Format: Article
Language:English
Published: BioMed Central 2024
Online Access:https://hdl.handle.net/1721.1/157518

Internet

https://hdl.handle.net/1721.1/157518

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