Mechanistic modeling of in vitro transcription incorporating effects of magnesium pyrophosphate crystallization
The in vitro transcription (IVT) reaction used in the production of messenger RNA vaccines and therapies remains poorly quantitatively understood. Mechanistic modeling of IVT could inform reaction design, scale‐up, and control. In this work, we develop a mechanistic model of IVT to include nucleatio...
| Main Authors: | , , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2024
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| Online Access: | https://hdl.handle.net/1721.1/157673 |