Polymer folding through active processes recreates features of genome organization

From proteins to chromosomes, polymers fold into specific conformations that control their biological function. Polymer folding has long been studied with equilibrium thermodynamics, yet intracellular organization and regulation involve energy-consuming, active processes. Signatures of activity have...

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Bibliographic Details
Main Authors: Goychuk, Andriy, Kannan, Deepti, Chakraborty, Arup K, Kardar, Mehran
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Format: Article
Language:English
Published: Proceedings of the National Academy of Sciences 2024
Online Access:https://hdl.handle.net/1721.1/157790