Glioblastoma-cortical organoids recapitulate cell state heterogeneity and intercellular transfer

Glioblastoma-cortical organoids recapitulate cell state heterogeneity and intercellular transfer

Glioblastoma is characterized by heterogeneous malignant cells that are functionally integrated within the neuroglial microenvironment. Here, we model this ecosystem by growing glioblastoma into long-term cultured human cortical organoids that contain the major neuroglial cell types found in the cer...

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Bibliographic Details
Main Authors: Mangena, Vamsi, Chanoch-Myers, Rony, Sartore, Rafaela, Paulsen, Bruna, Gritsch, Simon, Weisman, Hannah, Hara, Toshiro, Breakefield, Xandra O, Breyne, Koen, Regev, Aviv, Chung, Kwanghun, Arlotta, Paola, Tirosh, Itay, Suva, Mario L
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering
Format: Article
Language:English
Published: American Association for Cancer Research 2024
Online Access:https://hdl.handle.net/1721.1/157902

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https://hdl.handle.net/1721.1/157902

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