Protein codes promote selective subcellular compartmentalization

Protein codes promote selective subcellular compartmentalization

Cells have evolved mechanisms to distribute ~10 billion protein molecules to subcellular compartments where diverse proteins involved in shared functions must assemble. Here, we demonstrate that proteins with shared functions share amino acid sequence codes that guide them to compartment destinat...

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Bibliographic Details
Main Authors: Kilgore, Henry R., Chinn, Itamar, Mikhael, Peter G., Mitnikov, Ilan, Van Dongen, Catherine, Zylberberg, Guy, Afeyan, Lena, Banani, Salman F., Wilson-Hawken, Susana, Ihn Lee, Tong, Barzilay, Regina, Young, Richard A.
Other Authors: Whitehead Institute for Biomedical Research
Format: Article
Language:en_US
Published: American Association for the Advancement of Science 2025
Online Access:https://hdl.handle.net/1721.1/158180

Internet

https://hdl.handle.net/1721.1/158180

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