Crystalline Antibody‐Laden Alginate Particles: A Platform for Enabling High Concentration Subcutaneous Delivery of Antibodies

Crystalline Antibody‐Laden Alginate Particles: A Platform for Enabling High Concentration Subcutaneous Delivery of Antibodies

Subcutaneous (SC) administration is a desired route for monoclonal antibodies (mAbs). However, formulating mAbs for small injection volumes at high concentrations with suitable stability and injectability is a significant challenge. Here, this work presents a platform technology that combines the st...

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Bibliographic Details
Main Authors: Erfani, Amir, Schieferstein, Jeremy M, Reichert, Paul, Narasimhan, Chakravarthy N, Pastuskovas, Cinthia, Parab, Vaishali, Simmons, Denarra, Yang, Xiaoyu, Shanker, Apoorv, Hammond, Paula, Doyle, Patrick S
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering
Format: Article
Language:English
Published: Wiley 2025
Online Access:https://hdl.handle.net/1721.1/158280

Internet

https://hdl.handle.net/1721.1/158280

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