Active Hypothermic Growth: A Novel Means For Increasing Total Interferon-γ Production by Chinese Hamster Ovary Cells

When grown under hypothermic conditions, Chinese Hamster Ovary (CHO) cells become growth arrested in the G₀/G₁ phase of the cell cycle and also often exhibit increased recombinant protein production. In this study, we have validated this hypothesis by stimulating hypothermic growth using basic fibr...

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Bibliographic Details
Main Authors: Stephen R., Fox, Yap, Mei Xia, Yap, Miranda G.S., Wang, Daniel I.C.
Format: Article
Language:English
Published: 2005
Subjects:
Online Access:http://hdl.handle.net/1721.1/30379