Correlating Gene Transfection Efficiency and the Physical Properties of Various Cationic Poly(methacrylate) Systems

Transfection efficiencies of several polymeric gene carriers were compared and correlated quantitatively to the amounts of cellular accumulation of plasmid DNA and to the expression of mRNA by quantitative real time PCR. Three cationic methacrylate polymer systems with similar chemical structure wer...

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Bibliographic Details
Main Authors: Tan, J. F., Too, Heng-Phon, Hatton, T. Alan, Tam, K. C.
Format: Article
Language:English
Published: 2005
Subjects:
Online Access:http://hdl.handle.net/1721.1/30383