Engineering of bacterial strains and vectors for the production of plasmid DNA
The demand for plasmid DNA (pDNA) is anticipated to increase significantly as DNA vaccines and non-viral gene therapies enter phase 3 clinical trials and are approved for use. This increased demand, along with renewed interest in pDNA as a therapeutic vector, has motivated research targeting the des...
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Format: | Article |
Language: | en_US |
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Springer Berlin Heidelberg
2009
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Online Access: | http://hdl.handle.net/1721.1/49483 https://orcid.org/0000-0003-0437-3157 |