Engineering of bacterial strains and vectors for the production of plasmid DNA

The demand for plasmid DNA (pDNA) is anticipated to increase significantly as DNA vaccines and non-viral gene therapies enter phase 3 clinical trials and are approved for use. This increased demand, along with renewed interest in pDNA as a therapeutic vector, has motivated research targeting the des...

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Bibliographic Details
Main Authors: Prather, Kristala L. Jones, Bower, Diana Morgan
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering
Format: Article
Language:en_US
Published: Springer Berlin Heidelberg 2009
Subjects:
Online Access:http://hdl.handle.net/1721.1/49483
https://orcid.org/0000-0003-0437-3157