Bifunctional polymeric inhibitors of human influenza A viruses
Purpose. New antiviral agents were prepared by attaching derivatives of sialic acid (1) and of the drug zanamivir (2) to poly(isobutylene-alt-maleic anhydride) (poly-(1 + 2)) or by mixing poly-1 and poly-2, followed by assaying them against wild-type and drug-resistant influenza A Wuhan viruses. Me...
Main Authors: | Haldar, Jayanta, Alvarez de Cienfuegos, Luis, Tumpey, Terrence M., Gubareva, Larisa V., Chen, Jianzhu, Klibanov, Alexander M. |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology |
Format: | Article |
Language: | en_US |
Published: |
Springer Netherlands
2009
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Subjects: | |
Online Access: | http://hdl.handle.net/1721.1/49840 https://orcid.org/0000-0003-3830-714X https://orcid.org/0000-0002-5687-6154 |
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