Antibodies specifically targeting a locally misfolded region of tumor associated EGFR

Antibodies specifically targeting a locally misfolded region of tumor associated EGFR

Epidermal Growth Factor Receptor (EGFR) is involved in stimulating the growth of many human tumors, but the success of therapeutic agents has been limited in part by interference from the EGFR on normal tissues. Previously, we reported an antibody (mab806) against a truncated form of EGFR found comm...

Full description

Bibliographic Details
Main Authors: Garrett, Thomas P. J., Burgess, Anthony W., Gan, Hui K., Luwor, Rod B., Cartwright, Glenn, Walker, Francesca, Orchard, Suzanne G., Clayton, Andrew H. A., Nice, Edouard C., Rothacker, Julie, Catimel, Bruno, Cavenee, Webster K., Old, Lloyd J., Stockert, Elisabeth, Ritter, Gerd, Adams, Timothy E., Hoyne, Peter A., Wittrup, Karl Dane, Chao, Ginger, Cochran, Jennifer R., Lou, Cindy, Lou, Mezhen, Huyton, Trevor, Xu, Yibin, Fairlie, W. Douglas, Yao, Shenggen, Scott, Andrew M., Johns, Terrance G.
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering
Format: Article
Language:en_US
Published: National Academy of Sciences 2009
Online Access:http://hdl.handle.net/1721.1/50256
https://orcid.org/0000-0003-2398-5896

Internet

http://hdl.handle.net/1721.1/50256
https://orcid.org/0000-0003-2398-5896

Similar Items