Evolutionarily conserved recognition and innate immunity to fungal pathogens by the scavenger receptors SCARF1 and CD36

Receptors involved in innate immunity to fungal pathogens have not been fully elucidated. We show that the Caenorhabditis elegans receptors CED-1 and C03F11.3, and their mammalian orthologues, the scavenger receptors SCARF1 and CD36, mediate host defense against two prototypic fungal pathogens, Cryp...

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Bibliographic Details
Main Authors: Means, Terry K., Mylonakis, Eleftherios, Tampakakis, Emmanouil, Colvin, Richard A., Seung, Edward, Puckett, Lindsay, Tai, Melissa F., Stewart, Cameron R., Pukkila-Worley, Read, Hickman, Suzanne E., Moore, Kathryn J., Calderwood, Stephen B., Hacohen, Nir, Luster, Andrew D., El Khoury, Joseph
Other Authors: Broad Institute of MIT and Harvard
Format: Article
Language:en_US
Published: Rockefeller University Press 2010
Online Access:http://hdl.handle.net/1721.1/52003