Transforming Boolean models to continuous models: methodology and application to T-cell receptor signaling

Transforming Boolean models to continuous models: methodology and application to T-cell receptor signaling

Background The understanding of regulatory and signaling networks has long been a core objective in Systems Biology. Knowledge about these networks is mainly of qualitative nature, which allows the construction of Boolean models, where the state of a component is either 'off' or 'o...

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Bibliographic Details
Main Authors: Wittmann, Dominik M., Krumsiek, Jan, Saez-Rodriguez, Julio, Lauffenburger, Douglas A., Klamt, Steffen, Theis, Fabian J.
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: BioMed Central Ltd. 2010
Online Access:http://hdl.handle.net/1721.1/52311

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http://hdl.handle.net/1721.1/52311

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