Bridging the gap between high-throughput genetic and transcriptional data reveals cellular pathways responding to alpha-synuclein toxicity

Bridging the gap between high-throughput genetic and transcriptional data reveals cellular pathways responding to alpha-synuclein toxicity

Cells respond to stimuli by changes in various processes, including signaling pathways and gene expression. Efforts to identify components of these responses increasingly depend on mRNA profiling and genetic library screens, yet the functional roles of the genes identified by these assays often r...

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Bibliographic Details
Main Authors: Yeger-Lotem, Esti, Riva, Laura, Su, Linhui Julie, Gitler, Aaron D., Cashikar, Anil G., King, Oliver D., Auluck, Pavan K., Geddie, Melissa L., Valastyan, Julie Suzanne, Lindquist, Susan, Fraenkel, Ernest, Karger, David R
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory
Format: Article
Language:en_US
Published: Nature Publishing Group 2010
Online Access:http://hdl.handle.net/1721.1/52324
https://orcid.org/0000-0003-1307-882X
https://orcid.org/0000-0001-9249-8181
https://orcid.org/0000-0002-0024-5847

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http://hdl.handle.net/1721.1/52324
https://orcid.org/0000-0003-1307-882X
https://orcid.org/0000-0001-9249-8181
https://orcid.org/0000-0002-0024-5847

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