Bridging the gap between high-throughput genetic and transcriptional data reveals cellular pathways responding to alpha-synuclein toxicity
Cells respond to stimuli by changes in various processes, including signaling pathways and gene expression. Efforts to identify components of these responses increasingly depend on mRNA profiling and genetic library screens, yet the functional roles of the genes identified by these assays often r...
Main Authors: | Yeger-Lotem, Esti, Riva, Laura, Su, Linhui Julie, Gitler, Aaron D., Cashikar, Anil G., King, Oliver D., Auluck, Pavan K., Geddie, Melissa L., Valastyan, Julie Suzanne, Lindquist, Susan, Fraenkel, Ernest, Karger, David R |
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Other Authors: | Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory |
Format: | Article |
Language: | en_US |
Published: |
Nature Publishing Group
2010
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Online Access: | http://hdl.handle.net/1721.1/52324 https://orcid.org/0000-0003-1307-882X https://orcid.org/0000-0001-9249-8181 https://orcid.org/0000-0002-0024-5847 |
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