Dynamic fluctuations of protein-carbohydrate interactions promote aggregation
Protein-carbohydrate interactions are important for glycoprotein structure and function. Antibodies of the IgG class, with increasing significance as therapeutics, are glycosylated at a conserved site in the constant Fc region. We hypothesized that disruption of protein-carbohydrate interactions in...
| Main Authors: | , , , , , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
| Published: |
Public Library of Science
2010
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| Online Access: | http://hdl.handle.net/1721.1/52397 https://orcid.org/0000-0003-1417-9470 |