Whole genome amplification and de novo assembly of single bacterial cells

Whole genome amplification and de novo assembly of single bacterial cells

Background Single-cell genome sequencing has the potential to allow the in-depth exploration of the vast genetic diversity found in uncultured microbes. We used the marine cyanobacterium Prochlorococcus as a model system for addressing important challenges facing high-throughput whole genome ampl...

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Bibliographic Details
Main Authors: Rodrigue, Sebastien, Malmstrom, Rex R., Berlin, Aaron M., Birren, Bruce W., Henn, Matthew R., Chisholm, Sallie (Penny)
Other Authors: Massachusetts Institute of Technology. Department of Civil and Environmental Engineering
Format: Article
Language:en_US
Published: Public Library of Science 2010
Online Access:http://hdl.handle.net/1721.1/52439

Internet

http://hdl.handle.net/1721.1/52439

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