Identifying relationships among genomic disease regions: predicting= pathogenic SNP associations and rare deletions

Translating a set of disease regions into insight about pathogenic mechanisms requires not only the ability to identify the key disease genes within them, but also the biological relationships among those key genes. Here we describe a statistical method, Gene Relationships Among Implicated Loci (GRA...

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Bibliographic Details
Main Authors: Raychaudhuri, Soumya, Plenge, Robert M., Rossin, Elizabeth, Ng, Aylwin C. Y., Purcell, Shaun M., Sklar, Pamela, Scolnick, Edward Mark, Xavier, Ramnik J., Altshuler, David, Daly, Mark J.
Other Authors: Broad Institute of MIT and Harvard
Format: Article
Language:en_US
Published: Public Library of Science 2010
Online Access:http://hdl.handle.net/1721.1/52464
https://orcid.org/0000-0001-6757-5341