The l[subscript 1]-l[subscript 2] regularization framework unmasks the hypoxia signature hidden in the transcriptome of a set of heterogeneous neuroblastoma cell lines
Background: Gene expression signatures are clusters of genes discriminating different statuses of the cells and their definition is critical for understanding the molecular bases of diseases. The identification of a gene signature is complicated by the high dimensional nature of the data and by the...
Main Authors: | , , , , , |
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Other Authors: | |
Format: | Article |
Language: | en_US |
Published: |
BioMed Central
2010
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Online Access: | http://hdl.handle.net/1721.1/52504 https://orcid.org/0000-0001-6376-4786 |