The l[subscript 1]-l[subscript 2] regularization framework unmasks the hypoxia signature hidden in the transcriptome of a set of heterogeneous neuroblastoma cell lines

Background: Gene expression signatures are clusters of genes discriminating different statuses of the cells and their definition is critical for understanding the molecular bases of diseases. The identification of a gene signature is complicated by the high dimensional nature of the data and by the...

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Bibliographic Details
Main Authors: Varesio, Luigi, Verri, Alessandro, Mosci, Sofia, Barla, Annalisa, Fardin, Paolo, Rosasco, Lorenzo Andrea
Other Authors: Massachusetts Institute of Technology. Center for Biological & Computational Learning
Format: Article
Language:en_US
Published: BioMed Central 2010
Online Access:http://hdl.handle.net/1721.1/52504
https://orcid.org/0000-0001-6376-4786