Design of therapeutic proteins with enhanced stability

Therapeutic proteins such as antibodies constitute the most rapidly growing class of pharmaceuticals for use in diverse clinical settings including cancer, chronic inflammatory diseases, kidney transplantation, cardiovascular medicine, and infectious diseases. Unfortunately, they tend to aggregate w...

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Bibliographic Details
Main Authors: Kayser, Veysel, Voynov, Vladimir, Chennamsetty, Naresh, Trout, Bernhardt L., Helk, Bernhard
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering
Format: Article
Language:en_US
Published: United States National Academy of Sciences 2010
Online Access:http://hdl.handle.net/1721.1/52552
https://orcid.org/0000-0003-1417-9470