High-affinity lamprey VLRA and VLRB monoclonal antibodies

Lamprey are members of the ancestral vertebrate taxon (jawless fish), which evolved rearranging antigen receptors convergently with the jawed vertebrates. But instead of Ig superfamily domains, lamprey variable lymphocyte receptors (VLRs) consist of highly diverse leucine-rich repeats. Although VLRs...

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Bibliographic Details
Main Authors: Wittrup, Karl Dane, Pancer, Zeev, Mariuzza, Roy A., Flajnik, Martin F., Xu, Gang, Velikovsky, C. Alejandro, Tasumi, Satoshi, Gai, S. Annie
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: United States National Academy of Sciences 2010
Online Access:http://hdl.handle.net/1721.1/52559
https://orcid.org/0000-0003-2398-5896