Reduced expression of the Kinesin-Associated Protein 3 (KIFAP3) gene increases survival in sporadic amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis is a degenerative disorder of motor neurons that typically develops in the 6th decade and is uniformly fatal, usually within 5 years. To identify genetic variants associated with susceptibility and phenotypes in sporadic ALS, we performed a genome-wide SNP analysis in s...

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Bibliographic Details
Main Authors: Sapp, Peter C., Horvitz, Howard Robert
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: United States National Academy of Sciences 2010
Online Access:http://hdl.handle.net/1721.1/52562
https://orcid.org/0000-0002-9964-9613