Fibro-C-Index: comprehensive, morphology-based quantification of liver fibrosis using second harmonic generation and two-photon microscopy

We develop a standardized, fully automated, quantification system for liver fibrosis assessment using second harmonic generation microscopy and a morphology-based quantification algorithm. Liver fibrosis is associated with an abnormal increase in collagen as a result of chronic liver diseases. Histo...

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Bibliographic Details
Main Authors: Yu, Hanry, So, Peter T. C., Rajapakse, Jagath, Chen, Chien Shing, Tang, Hui-Huan, Chang, Shi, Xiao, Guangfa, Raja, Anju Mythreyi, Wei, Chiang Li, Wee, Aileen, Cheng, Chee Leong, Chia, Ser-Mien, Kang, Chiang Huen, Xu, Shuoyu, Tan, Nancy, Tai, Dean C. S.
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Society of Photo-Optical Instrumentation Engineers 2010
Online Access:http://hdl.handle.net/1721.1/52631
https://orcid.org/0000-0002-0339-3685
https://orcid.org/0000-0003-4698-6488