IL-3 and Oncogenic Abl Regulate the Myeloblast Transcriptome by Alt= Stability

IL-3 and Oncogenic Abl Regulate the Myeloblast Transcriptome by Alt= Stability

The growth factor interleukin-3 (IL-3) promotes the survival and growth of multipotent hematopoietic progenitors and stimulates myelopoiesis. It has also been reported to oppose terminal granulopoiesis and to support leukemic cell growth through autocrine or paracrine mechanisms. The degree to whi...

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Bibliographic Details
Main Authors: Ernst, Jason, Ghanem, Louis, Bar-Joseph, Ziv, McNamara, Michael, Brown, Jason, Steinman, Richard A.
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory
Format: Article
Language:en_US
Published: Public Library of Science 2010
Online Access:http://hdl.handle.net/1721.1/52709

Internet

http://hdl.handle.net/1721.1/52709

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