Redox signaling between DNA repair proteins for efficient lesion detection

Base excision repair (BER) enzymes maintain the integrity of the genome, and in humans, BER mutations are associated with cancer. Given the remarkable sensitivity of DNA-mediated charge transport (CT) to mismatched and damaged base pairs, we have proposed that DNA repair glycosylases (EndoIII and Mu...

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Bibliographic Details
Main Authors: Barton, Jacqueline K., Gralnick, Jeffrey A., Sontz, Pamela A., Genereux, Joseph C., Boal, Amie K., Newman, Dianne K
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: United States National Academy of Sciences 2010
Online Access:http://hdl.handle.net/1721.1/54715