Epigenetic and conventional regulation is distributed among activat= allowing tuning of population-level heterogeneity in its expression

Epigenetic switches encode their state information either locally, often via covalent modification of DNA or histones, or globally, usually in the level of a trans-regulatory factor. Here we examine how the regulation of cis-encoded epigenetic switches controls the extent of heterogeneity in gene...

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Bibliographic Details
Main Authors: Octavio, Leah M., Gedeon, Kamil S., Maheshri, Narendra
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Public Library of Science 2010
Online Access:http://hdl.handle.net/1721.1/54763