Epigenetic and conventional regulation is distributed among activat= allowing tuning of population-level heterogeneity in its expression
Epigenetic switches encode their state information either locally, often via covalent modification of DNA or histones, or globally, usually in the level of a trans-regulatory factor. Here we examine how the regulation of cis-encoded epigenetic switches controls the extent of heterogeneity in gene...
Main Authors: | Octavio, Leah M., Gedeon, Kamil S., Maheshri, Narendra |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology |
Format: | Article |
Language: | en_US |
Published: |
Public Library of Science
2010
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Online Access: | http://hdl.handle.net/1721.1/54763 |
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