Nitric oxide activation of Keap1/Nrf2 signaling in human colon carcinoma cells

The transcription factor NF-E2-related nuclear factor 2 (Nrf2) regulates expression of genes that protect cells from oxidative damage. Here, we characterized nitric oxide (•NO)-induced Nrf2–Kelch-like ECH-associated protein 1 (Keap1) signaling and its role in counteracting •NO-induced apoptosis of h...

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Detalhes bibliográficos
Principais autores: Wogan, Gerald N., Trudel, Laura J., Thiantanawat, Apinya, Godoy, Luiz Claudio, Kim, Min Young, Lia, Chun-Qi
Outros Autores: Massachusetts Institute of Technology. Department of Biological Engineering
Formato: Artigo
Idioma:en_US
Publicado em: United States National Academy of Sciences 2010
Acesso em linha:http://hdl.handle.net/1721.1/54795
https://orcid.org/0000-0003-0771-9889