Silencing of tryptamine biosynthesis for production of nonnatural alkaloids in plant culture

Natural products have long served as both a source and inspiration for pharmaceuticals. Modifying the structure of a natural product often improves the biological activity of the compound. Metabolic engineering strategies to ferment “unnatural” products have been enormously successful in microbial o...

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Bibliographic Details
Main Authors: O'Connor, Sarah Ellen, Maresh, Justin J., Runguphan, Weerawat
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Language:en_US
Published: United States National Academy of Sciences 2010
Online Access:http://hdl.handle.net/1721.1/54798