Myc Is Required for Activation of the ATM-Dependent Checkpoints in Response to DNA Damage

Background: The MYC protein controls cellular functions such as differentiation, proliferation, and apoptosis. In response to genotoxic agents, cells overexpressing MYC undergo apoptosis. However, the MYC-regulated effectors acting upstream of the mitochondrial apoptotic pathway are still unknown. P...

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Bibliographic Details
Main Authors: Guerra, Lina, Albihn, Ami, Tronnersjö, Susanna, Yan, Qinzi, Guidi, Riccardo, Stenerlöw, Bo, Sterzenbach, Torsten, Josenhans, Christine, Fox, James G., Schauer, David B., Thelestam, Monica, Larsson, Lars-Gunnar, Henriksson, Marie, Frisan, Teresa
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Public Library of Science 2010
Online Access:http://hdl.handle.net/1721.1/55379
https://orcid.org/0000-0001-9307-6116