Myc Is Required for Activation of the ATM-Dependent Checkpoints in Response to DNA Damage
Background: The MYC protein controls cellular functions such as differentiation, proliferation, and apoptosis. In response to genotoxic agents, cells overexpressing MYC undergo apoptosis. However, the MYC-regulated effectors acting upstream of the mitochondrial apoptotic pathway are still unknown. P...
Main Authors: | , , , , , , , , , , , , , |
---|---|
Other Authors: | |
Format: | Article |
Language: | en_US |
Published: |
Public Library of Science
2010
|
Online Access: | http://hdl.handle.net/1721.1/55379 https://orcid.org/0000-0001-9307-6116 |