Loss of Hsp70 Exacerbates Pathogenesis But Not Levels of Fibrillar Aggregates in a Mouse Model of Huntington's Disease
Endogenous protein quality control machinery has long been suspected of influencing the onset and progression of neurodegenerative diseases characterized by accumulation of misfolded proteins. Huntington's disease (HD) is a fatal neurodegenerative disorder caused by an expansion of a polygl...
| Autors principals: | , , , , , , , , , , |
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| Altres autors: | |
| Format: | Article |
| Idioma: | en_US |
| Publicat: |
Society for Neuroscience
2010
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| Accés en línia: | http://hdl.handle.net/1721.1/56557 https://orcid.org/0000-0003-1307-882X |